In December I realized that I was badly depressed, so I asked my psychiatrist to prescribe imipramine. As a very old antidepressant, it is not commonly used anymore, but my experience is that it works well for me.
I haven't been able to find work so what little money I get, I earn by singing on the street for tips. I had a setback when I got bronchitis, and could not raise the money for bus fare to get to my pharmacy. That led to my getting depressed again.
I went to the emergency room, they set me up with one dose and a bus ticket. Now I'm back on track. For quite a long time, I would get into these really foul states of mind. Now it has been two or three weeks since the last time that happened.
I can tell that I'm still somewhat depressed but in general life is a lot better. Antidepressants are always slow to take effect. One has to establish new patterns in one's life.